Major Cities Of Florida. The city is sprawled along three winding rivers with several sweeping bridges that span their waters. Florida's largest cities by population jacksonville, fl.
The major cities in florida are jacksonville, miami, tampa, orlando, st. Scroll down the page to see a longer list of smaller cities. Located on the southwest coast of florida, the city has lots of great restaurants and shopping malls to attract visitors, as well as some beautiful beaches, with siesta bay beach considered one of the best in florida.